S-Acetyl Glutathione Supplement for Potential Antioxidant Support*

S-acetyl glutathione (SAG) is an acetylated form of glutathione, designed to help protect the molecule during digestion so it can help maintain the body's antioxidant defenses.*

What Is Glutathione?

Reduced glutathione, commonly known as glutathione or GSH, is a tripeptide made up of three amino acids: glutamic acid, L-cysteine, and glycine. It is naturally present in all living cells. Glutathione levels can vary with oxidative stress, diet, and individual factors, such as each person's ability to use its building blocks.

Glutathione appears to be considered as one of the most important antioxidants produced inside the body's cells. Standard glutathione taken by mouth is easily broken down during digestion, which is why acetylated forms such as SAG were developed.*

What Are the Potential Benefits of S-Acetyl Glutathione?*

In this acetylated form, glutathione may help:*

• Support mitochondrial function and cellular energy.* Mitochondria are the energy-producing structures of cells and also the main site where reactive oxygen species (ROS) are formed. Early research suggests SAG may reach the mitochondria and help maintain their integrity by supporting a healthy balance of ROS.*
• Help protect cells from oxidative stress.* Glutathione is a central part of the body's natural antioxidant system, which might help maintain the integrity of cells and their DNA.*
• Support already healthy oxidative stress markers.* Studies have looked at the effect of SAG on markers of oxidative stress, such as F2-isoprostanes.*

Research also suggests that glutathione levels in certain immune cells, such as macrophages, may play a role in a balanced immune response.*

Why Choose an S-Acetyl Glutathione Supplement?

S-acetyl glutathione carries an acetyl group that seems to help protect the molecule from breaking down during digestion.* Once inside cells, natural enzymes remove this acetyl group and release reduced glutathione.* This may help support the body's glutathione levels, its antioxidant defenses in all tissues, and normal immune function.*

To complement SAG, SuperSmart also offers:

• N-Acetyl Cysteine (NAC), a form of the amino acid L-cysteine. Like methionine, it contains a sulfur atom and serves as a building block for the body's own glutathione production.*
• Other amino acids, such as Lysine and Branched-Chain Amino Acids (BCAAs) with leucine, isoleucine, and valine, may also contribute to the synthesis of important molecules.*
• SAG may also complement our two other forms of glutathione, Perlingual Glutathione and Reduced Glutathione. Together, they offer different ways to support glutathione levels as part of a daily wellness routine.*

If you are following conventional approaches, speak with your healthcare professional, who can review your history and any possible interactions.

S-Acetyl Glutathione capsules can be a simple addition to a healthy aging routine.*

As with any nutritional supplement, you should always consult a healthcare professional before use.