Our AMPK supplement is an innovative formulation that combines the most effective activators – or reactivators – of cellular AMP-activated protein kinase, also known as AMPK, and promotes health and longevity.
Inside each of our cells is a key metabolism enzyme called AMPK (adenosine monophosphate-activated protein kinase), which plays a fundamental role in energy homeostasis and supports longevity, essentially.
AMPK is expressed in a number of body parts – the liver, the brain, and muscles – where it functions like a metabolic master switch, regulating several intracellular systems.
AMPK benefits, more specifically, are as follows:
As studies show, boosting the activity of AMPK can have several positive effects on the body. Our AMPK supplement is designed to activate or reactivate AMPK via the action of barberry, jiaogulan, and Rhus succedanea. Together, these constitute a natural, effective formulation for supporting overall health.
You may also be interested in two other natural extracts available to buy at SuperSmart for improving your general state of health and combating the aging process: Astragalus Extract and Reishi Extract.
Restoring AMPK enzyme activity may not only help you recapture a certain youthfulness; it may also help you combat the development of excess fat. When you boost AMPK, cells are thrown into survival mode and stop storing new fat. Instead, they burn stored fat – similar to what a calorie restriction does.
As far as how to boost AMPK, our AMPK Booster supplement combines three plant extracts able to reactivate this cellular enzyme. Those three ingredients are as follows:
What is gynostemma pentaphyllum?
Gynostemma pentaphyllum (or jiaogulan), standardized in gypenosides, has also demonstrated AMPK-activating capacity. Used in traditional Asian medicine, this plant is sometimes called the "immortality herb," both because it increases longevity and has a number of other properties conferring antioxidant, adaptogen and anti-atherosclerotic effects.
Gynostemma pentaphyllum has been heavily researched:
Combined, these results show how the activation of AMPK produces huge benefits in reducing circulating sugar and fats. And human studies have found similar results: gynostemma pentaphyllum boosts AMPK activity, which may lead to certain long-term health benefits.
Our natural AMPK activator also contains fisetin, a flavonoid extracted from Rhus succedanea that sends a switch-on signal (like epitalon) to longevity transporter genes in a way similar to calorie restriction but without the need to make dietary changes.
Berberine (Berberis vulgaris), an isoquinoline alkaloid, scientifically demonstrated to be one of the best AMPK-activators, which acts on a number of parameters.
Further confirmation of berberine's AMPK-activating efficacy comes from recent studies that showed it promoted the multimerization of adiponectin in adipocytes into high molecular weight (HMW) multimers. These have greater metabolic activity and are closely associated with pancreatic hormone sensitivity of cells.
Even though berberine inhibits adiponectin expression, its activation of AMPK promotes multimerization of adiponectin and thus helps combat the development of excess fat.
More specifically, berberine:
As we get older, activation of cellular AMPK declines. This can spur the development of surplus fat, as AMPK determines body fat composition. In order to combat the aging process, it is therefore essential to restore AMPK production, and there are various ways of doing this, such as physical exercise and calorie restriction, in addition to supporting those efforts with the right dietary supplements.
Most Western societies today are facing a significant problem with over-consumption. Eating too many calories impairs vital functions, such as healthy uptake of glucose and fat from the blood and leads to the accumulation of cellular waste and changes to longevity genes.
Oftentimes, this results in the development of surplus fat. Few people are able to successfully maintain long-term calorie restriction, and so the research by scientists of AMPK activation supplements is extremely helpful. When activated, this cellular enzyme mimics calorie restriction and may even lead to a decrease in body fat. Pre-clinical research has shown that boosting AMPK activity is associated with:
As more research is performed, we expect to learn more benefits of AMPK booster supplements.
You want the strongest AMPK activator to achieve maximum benefits, but it is also important to understand any possible side effects of jiaogulan AMPK products. While our AMPK supplement is considered safe for most healthy adults, it's still important to do your own research.
Talk to your healthcare provider before you start taking an AMPK activator berberine gynostemma la-3 supplement. Your physician will want to know what products are in the AMPK activator supplement and will determine how it may interact with other supplements, prescriptions or health issues you have.
If you notice any strange symptoms after you start taking a gynostemma pentaphyllum AMPK supplement, you should stop using it immediately and talk to your healthcare provider.
Additionally, there has been minimal research related to pregnant or breastfeeding women taking AMPK boosters. For this reason, we advise against taking them unless otherwise directed by your doctor.
Do not exceed the recommended daily dose. This product is a nutritional supplement and should not be used as a substitute for a varied and balanced diet or a healthy lifestyle.
Store in a cool, dry place away from direct sunlight, heat, and humidity. Keep out of reach of children.
If you are pregnant, breastfeeding, or have any medical conditions, consult your healthcare provider before using this product.
Consult your healthcare provider before use, especially if you are taking any medications or other supplements as there may be potential interactions.