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Bacopa monnieri
Bacopa monnieri
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Description

Bacopa monnieri is a nootropic supplement made from Bacopa leaves.

  • Helps improve memory, learning capacity, and information processing.
  • Supports central nervous system function.
  • Has a positive effect on the hippocampus.
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Bacopa monnieri plant branch

Bacopa Monnieri Capsules for Healthy Brain Activity

Inspired by the sacred practices of Ayurveda, Bacopa monnieri is a nootropic supplement in vegetarian capsules, made from Bacopa leaves and standardized to 20% bacosides (the chemical compounds responsible for its nootropic effects).

It helps improve memory, learning capacity, and information processing while supporting the whole central nervous system function. It is often combined with Ginkgo biloba, another 'gold-standard' in Ayurvedic medicine.

Who Should Take Bacopa Monnieri Supplements?

Bacopa monnieri is aimed at many groups of people:

  • Those over 50 who want to combat cognitive decline;
  • Those who frequently experience recall problems and feel as if they are losing their memory;
  • Those wishing to boost their cognitive function;
  • Those looking for a natural-source, traditionally used nootropic;
  • Those with a parent, brother, or sister affected by serious cognitive decline.

What Benefits does Bacopa Monnieri Offer?

According to ancient Ayurvedic writings, Bacopa monnieri was recommended for various conditions of the central nervous system and mind: attention deficit, memory problems, chronic stress, decline in cognitive performance, etc. Bacopa monnieri benefits were used to stimulate awareness and help maintain an alert mind.

Today, research is beginning to confirm such anecdotal use. Many studies, including clinical trials, suggest that extracts of organic Bacopa monnieri help improve certain cognitive functions and maintain memory (1-3) (retrieval of information (4-5), learning capacity, associative memory (6), visual memory, work memory, etc.).

As is the case for almost all Ayurvedic plants, scientists have discovered mechanisms of action that support the claims made for this nootropic.

Bacopa monnieri's mechanisms of action

Bacopa monnieri primarily encourages the formation of synapses (7-9), the junctions between two neurons that ensure that information is transmitted and neural circuits are maintained. All our cognitive abilities depend on these circuits: if they become weak or disappear, our performance declines.

How does Bacopa monnieri do this?

It is by triggering the production of several molecules central to healthy synaptic function: glutamate and neutrophils such as BDNF and NGF (10-12). These molecules are crucial for initiating the process (13-14). They support the creation of neural circuits (an essential learning stage), help maintain existing circuits (vital for preserving memories), and are involved in a cascade of neuromolecular events that support cognitive performance.

Recent double-blind trials showed improvements in cognitive function following supplementation (15-16). Standardized extracts of Bacopa containing at least 20% bacosides (the compounds responsible for the previously mentioned effects) have also positively affected short-term memory in healthy individuals (17-20).

5 Good Reasons to Choose Bacopa Monnieri from SuperSmart

When deciding which Bacopa monnieri supplement to buy, be sure to keep in mind the benefits offered by our product:

  1. Bacopa monnieri is 100% inspired by ancient practice. Bacopa leaves were traditionally pressed to extract the juice, which was then dried into a powder and made into a very sweet syrup to mask the bitter taste of the Bacopa. Though inspired by this ancient practice, Bacopa monnieri is a product with neither sugar nor bitterness.
  2. Bacopa monnieri is a leaf extract that contains all the naturally occurring compounds. It is important to remember that many cheaper alternatives to Bacopa monnieri leaf extract are made from the plant's roots or stems.
  3. The vegetarian Bacopa capsules contain 100 mg of Bacopa monnieri extract each, standardized to provide at least 20% bacosides.
  4. In India, Bacopa is currently recognized by medical authorities as a valid treatment for several types of mental and intellectual dysfunction.
  5. Bacopa monnieri contains no chemical bulking agents: just Bacopa monnieri leaves.

Additional Measures to Make Bacopa Monnieri Extract Even More Effective

There are two types of intervention for improving aspects of cognition: taking nootropics such as Bacopa monnieri and brain training (21-23). A large number of studies show that brain training reduces age-related cognitive decline (24-27), and some suggest it is even more effective when combined with Bacopa monnieri supplementation.

The theory behind this potential synergy is quite simple.

Brain training reactivates neural circuits that were previously under-exploited or were in decline (28-30). As we age, many neural circuits disappear or become weaker in brain areas important for cognition and memory, such as the hippocampus, the striatum, and the prefrontal cortex (31-32). When brain training is practiced frequently, it repeatedly reactivates these circuits and improves the connection between the neurons of which they are composed (33). As a result, it helps boost or reorganize them more effectively. This reinforcement involves several molecules mentioned earlier in this article: glutamate, BDNF, and TGF; molecules whose production is promoted by Bacopa.

In other words, brain training is the stimulus that signals to the body that it is time to boost its neural circuits. Bacopa is the supplier, providing the elements it needs to do so.

It is therefore highly recommended that alongside supplementation with Bacopa monnieri, brain training, such as puzzles, brain teasers, and a range of cognitive tasks, is practiced regularly. This combined approach aims to counteract the cognitive losses that lead to decline. It needs to be maintained for at least 12 weeks to be effective.

Bacopa monnieri can also be combined with Ginkgo biloba to increase blood supply to the brain and help maintain cognitive function.

If you are interested in other natural Ayurvedic products available to buy at SuperSmart, you may wish to consider:

  • An extract of Centella asiatica, traditionally used as a psychotropic to relieve mental fatigue.
  • An extract of Boswellia serrata with an anti-inflammatory effect that may benefit the central nervous system.
  • A Tribulus terrestris supplement (Tribulus terrestris), a plant which promotes healthy circulation and is traditionally used for stimulating the libido.

Are there any Precautions to be Taken or Interactions to be Aware of?

As a precautionary measure and before you decide to buy Bacopa monnieri, note that this supplement is not recommended for women who are pregnant or breastfeeding. Bacopa monnieri can, in theory, increase the effects of phenothiazine, a neuroleptic drug.

Note: this product should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. It is important to follow the guidelines on how to take it and the recommended dose and to use it by the 'best before' date. It is not recommended for pregnant or breastfeeding women or children under 15. Keep out of children's reach. Store in a cool, dry place.

Potential Side Effects of Bacopa Monnieri Extract

Before you decide to take nutritional supplements, including Bacopa Monnieri, it is highly recommended that you first prioritize thorough research on potential Bacopa monnieri extract side effects. Bacopa Monnieri is considered as safe for most people when taken at recommended doses, although certain individuals may sometimes experience adverse effects.

Bacopa monnieri extract side effects can vary widely from person to person. You must consult your healthcare provider before you decide to buy Bacopa Monnieri online and incorporate it into your regular regimen of nutritional supplements.

Additionally, it is important to emphasize that having a firm understanding of the potential side effects of nutritional supplements can help you monitor your body's response and make necessary adjustments. Overall, research and consultation with healthcare experts are indispensable steps to ensure your well-being and safety when considering using Bacopa Monnieri or any other dietary supplement.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Composition
Daily serving: 6 capsules
Number of servings per bottle: 16
Quantity per serving
Bacopa monnieri (leaf extract standardized to provide 20% bacosides) 1,500 mg
Other ingredient: acacia gum.

Each vegetarian capsule contains 250 mg of Bacopa monnieri extract standardized to provide at least 20% baccosides.
Directions for use

How to Take our Bacopa Monnieri Capsules?

When individuals purchase Bacopa monnieri capsules with nootropic properties, following recommended guidelines to maximize their benefits is crucial. We recommend adults to take 1 or 2 vegetarian capsules, one to three times a day. Bacopa monnieri is renowned for its cognitive-enhancing effects and is typically taken as a dietary supplement. Here's a concise guide on how to use these capsules effectively:

  1. Dosage: start with the recommended dosage provided on the product label, or consult with a healthcare professional for personalized advice. Standard dosages are usually between 300 and 600 mg per day, divided into two doses.
  2. Timing: take Bacopa monnieri capsules with a meal or a source of dietary fat to enhance absorption, as it is fat-soluble. Consistency is key, so aim to take it at the same time daily.
  3. Hydration: stay adequately hydrated throughout the day, as Bacopa may cause mild dehydration in some individuals.
  4. Patience: Bacopa monnieri's effects are cumulative, and it may take a few weeks to notice improvements in memory, focus, and cognitive function. Be patient and consistent in your usage.
  5. Monitor effects: pay attention to any changes in mood, energy, or sleep patterns. Adjust the dosage if necessary and consult a healthcare professional if you experience adverse effects.

In summary, those seeking to benefit from Bacopa monnieri capsules as a nootropic should follow the recommended dosage, stay consistent, and be patient in expecting results. Always consult a healthcare provider before starting any new supplement regimen, especially if you have underlying health conditions or are taking medication.

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References
  1. S. Aguiar and T. Borowski, Neuropharmacological review of the nootropic herb Bacopa monnieri, Rejuvenation Res 16 (2013), pp. 313-326.
  2. M.P. Pase, J. Kean, J. Sarris, C. Neale, A.B. Scholey and C. Stough, The cognitiveenhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials, J Altern Complement Med 18 (2012), pp. 647-652.
  3. Russo and F. Borrelli, Bacopa monniera, a reputed nootropic plant: an overview, Phytomedicine 12 (2005), pp. 305-317.
  4. H.C. Barbhaiya, R.P. Desai, K. Pravina, et al., Efficacy and tolerability of BacoMind on memory improvement in elderly participants - a double blind placebo controlled study, J Pharmacol Toxicol 3 (2008), pp. 425-434.
  5. C. Stough, J. Lloyd, J. Clarke, et al., The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects, Psychopharmacology (Berl) 156 (2001), pp. 481-484.
  6. S. Roodenrys, D. Booth, S. Bulzomi, A. Phipps, C. Micallef and J. Smoker, Chronic effects of Brahmi (Bacopa monnieri) on human memory, Neuropsychopharmacology 27 (2002), pp. 279-281.
  7. S.R. Ingole, S.K. Rajput and S.S. Sharma, Cognition enhancers: current strategies and future perspectives, CRIPS 9 (2008), pp. 42-48.
  8. P. Semwal, T. Kapoor, P. Anthwal, B. Sati and A. Thapliyal, Herbal extract as potential modulator and drug for synaptic plasticity and neurodegenerative disorders, Int J Pham Sci Rev Res 25 (2014), pp. 69-79.
  9. C. Stough and M.P. Pase, Improving cognition in the elderly with nutritional supplements, Curr Dir Psychol Sci 24 (2015), pp. 177-183.
  10. J. Preethi, H.K. Singh, P.D. Charles and K.E. Rajan, Participation of microRNA 124- CREB pathway: a parallel memory enhancing mechanism of standardised extract of Bacopa monniera (BESEB CDRI-08), Neurochem Res 37 (2012), pp. 2167-2177.
  11. H. Priyanka, P. Bala, S. Ankisettipalle and S. Thyagarajan, Bacopa monnieri and lDeprenyl Differentially Enhance the Activities of Antioxidant Enzymes and the Expression of Tyrosine Hydroxylase and Nerve Growth Factor via ERK 1/2 and NF- [kappa]B Pathways in the Spleen of Female Wistar Rats, Neurochemical Research 38 (2013), pp. 141-152.
  12. M.P. Mattson, R.B. Lee, M.E. Adams, P.B. Guthrie and S.B. Kater, Interactions between Entorhinal Axons and Target Hippocampal Neurons: A Role for Glutamate in the Development of Hippocampal Circuitry, Neuron 1 (1988), pp. 865-876.
  13. Schmid, S. Hallermann, R. Kittel, et al., Activity-dependent site-specific changes of glutamate receptor composition in vivo, Nat. Neurosci. 11 (2008), pp. 659-666.
  14. M.P. Pase, J. Kean, J. Sarris, C. Neale, A.B. Scholey and C. Stough, The cognitiveenhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials, J Altern Complement Med 18 (2012), pp. 647-652.
  15. C. Neale, D. Camfield, J. Reay, C. Stough and A. Scholey, Cognitive effects of two nutraceuticals Ginseng and Bacopa benchmarked against modaf.: a review and comparison of effect sizes, Br J Clin Pharmacol 75 (2013), pp. 728-737.
  16. Stough C, Lloyd J, et al. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects.Psychopharmacology (Berl). 2001 Aug;156(4):481-4.
  17. Roodenrys S, Booth D, et al. Chronic effects of Brahmi (Bacopa monnieri) on human memory.Neuropsychopharmacology. 2002 Aug;27(2):279-81.
  18. Examining the nootropic effects of a special extract of Bacopa monniera on human cognitive functioning: 90 day double-blind placebo-controlled randomized trial. Stough C, Downey LA, et al. Phytother Res. 2008 Dec;22(12):1629-34.
  19. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. Calabrese C, Gregory WL, et al. J Altern Complement Med. 2008 Jul;14(6):707-13.
  20. C. Hertzog, A.F. Kramer, R.S. Wilson and U. Lindenberger, Enrichment Effects on Adult Cognitive Development: Can the Functional Capacity of Older Adults Be Preserved and Enhanced?, Psychol. Sci. Public Interest 9 (2008), pp. 1-65.
  21. S. Rabipour and A. Raz, Training the brain: fact and fad in cognitive and behavioral remediation, Brain Cogn 79 (2012), pp. 159-179.
  22. Zangara and K.A. Wesnes, Herbal Cognitive Enhancers: New Developments and Challenges for Therapeutic Applications In: M.K. Thakur and S.I.S. Rattan, Editors, Brain Aging and Therapeutic Interventions, Springer Netherlands (2012), pp. 267- 289.
  23. J. Reijnders, C. van Heugten and M. van Boxtel, Cognitive interventions in healthy older adults and people with mild cognitive impairment: a systematic review, Ageing Res Rev 12 (2013), pp. 263-275.
  24. M.E. Kelly, D. Loughrey, B.A. Lawlor, I.H. Robertson, C. Walsh and S. Brennan, The impact of cognitive training and mental stimulation on cognitive and everyday functioning of healthy older adults: a systematic review and meta-analysis, Ageing Res Rev 15 (2014), pp. 28-43.
  25. A.M. Kueider, J.M. Parisi, A.L. Gross and G.W. Rebok, Computerized cognitive training with older adults: a systematic review, PLoS One 7 (2012), p. e40588.
  26. M. Martin, L. Clare, A.M. Altgassen, M.H. Cameron and F. Zehnder, Cognitionbased interventions for healthy older people and people with mild cognitive impairment, Cochrane Database Syst Rev (2011), p. CD006220.
  27. J.A. Anguera, J. Boccanfuso, J.L. Rintoul, et al., Video game training enhances cognitive control in older adults, Nature 501 (2013), pp. 97-101.
  28. K.I. Erickson, S.J. Colcombe, R. Wadhwa, et al., Training-induced plasticity in older adults: effects of training on hemispheric asymmetry, Neurobiol Aging 28 (2007), pp. 272-283.
  29. S. Heinzel, R.C. Lorenz, W.R. Brockhaus, et al., Working memory load-dependent brain response predicts behavioral training gains in older adults, J Neurosci 34 (2014), pp. 1224-1233.
  30. D.L. Dickstein, C.M. Weaver, J.I. Luebke and P.R. Hof, Dendritic spine changes associated with normal aging, Neuroscience 251 (2013), pp. 21-32.
  31. T. Hedden, Imaging Cognition in the Aging Human Brain In: D.R. Riddle, Editor, Brain Aging: Models, Methods, and Mechanisms, CRC Press, Boca Raton (FL) (2007).
  32. K.I. Erickson, S.J. Colcombe, R. Wadhwa, et al., Training-induced plasticity in older adults: effects of training on hemispheric asymmetry, Neurobiol Aging 28 (2007), pp. 272-283.

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